Perinatal outcomes in pregnant women with COVID-19 in Siberia and the Russian Far East.

OBJECTIVE: To assess the incidence and perinatal outcomes of COVID-19 in pregnant women in the Far Eastern and Siberian Federal Districts of Russian Federation over 10 months of a pandemic. MATERIALS AND METHODS: This was secondary analysis of Public Data basis on 25 Dec 2020. Statistics included descriptive statistics, analysis of contingency tables, which assessed the value of χ2, the achieved significance level (p). RESULTS: During the first year of the SARS-CoV-2 pandemic, 8485 cases of COVID-19 were registered in pregnant women in the Far Eastern Federal District and the Siberian Federal District, accounting for 5.9% of registered pregnant women and 1.71% of the total affected population. The morbidity rate in pregnant women was 3.02 times higher than in the general population: 5933.2 vs 1960.8 per 100 thousand population. 27.4% of mothers had asymptomatic disease; 52.7% - mild; 16.6% - moderate, 2.5% - severe, 0.5% - critical disease. The incidence of hospitalization in ICU of pregnant women was higher relative to the general population (3.57% vs 2.24%, p < .001), but the frequency of mechanical ventilation was lower (0.48% vs 1.05%, p < .001). Preterm delivery had 18.3% (p < .001 CS - 42.0%. The mortality rate in pregnant women was 0.14% vs 1.95% - in the general population (p < .001). Perinatal mortality was 37 cases (1.56%), of which there were 31 stillbirths (1.26%), and 6 (0.25%) cases of early neonatal mortality. 148 (6.2%) COVID-19(+) newborns were identified, despite anti-epidemic measures. CONCLUSION: The incidence of COVID-19 in pregnant women in Siberia and the Far East is higher than in the general population, but the disease is characterized by a milder. Women with COVID-19 have a high rate of preterm birth and CS. 148 (6.2%) newborns isolated COVID-19.

Recurrent group A streptococcal severe sepsis in the postpartum period.

This report presents the relapse and treatment of streptococcal infection in the postpartum period in a patient with severe group A streptococcal sepsis.